Built by clinicians, for clinicians

AI-native clinical intelligence for oncology

Zen Oncology brings autonomous AI agents, clinical decision support, and treatment pathway automation to cancer care — designed from the ground up for the complexity oncology demands.

Oncology is too complex for generic EHRs

Treatment pathways in oncology involve multi-agent regimens, response-driven branching, staging assessments, and coordination across dozens of specialists. Current EHRs weren't built for this.

Clinicians spend hours navigating systems that fight them at every step — clicking through workflows designed for primary care while managing CAR-T timelines, NCCN pathways, and life-or-death treatment decisions.

50%
of oncologists report burnout driven by EHR burden
2hrs
of after-hours EHR work per day, on average
62%
say their EHR does not support clinical decision-making
11+
clicks to complete a single chemo order in most systems

AI-native, not AI-added

Most EHRs bolt AI onto workflows built decades ago. Zen Oncology is engineered from the ground up with autonomous agents as a first-class architectural layer.

Oncology-First Data Model

Purpose-built for cancer care complexity — NCCN pathways, staging systems, multi-cycle regimens, and response-driven treatment branching are native to the schema, not afterthoughts.

Agentic AI Workflows

Autonomous clinical agents that reason over patient data, propose orders, surface literature, and check drug safety — augmenting clinicians rather than replacing their judgment.

Clinical Decision Support

Guideline-driven algorithms that track patients through treatment pathways, automate staging assessments, and surface the right decision at the right time.

HIPAA-Compliant by Design

End-to-end security architecture with MFA, session management, audit logging, PHI tokenization, role-based access control, and consent management baked in from day one.

Medication Safety

Integrated drug interaction checking, allergy verification, formulary management, and safety guardrails — with full support for complex oncology agents including cell and gene therapies.

FHIR-Ready Interoperability

Built on FHIR R4 resource mappings from the start, designed for seamless integration with existing health system infrastructure when the time comes.

Built for the full oncology workflow

From initial workup through treatment, response assessment, and long-term surveillance.

Treatment Pathway Engine

NCCN-aligned algorithm graphs with automated patient state tracking, transition criteria evaluation, and response-driven branching.

CAR-T Cell Therapy

End-to-end coordination for cellular therapies — from leukapheresis through manufacturing, conditioning, infusion, and long-term monitoring.

Clinical Agent Framework

ReAct-loop agents with tool use, citation tracking, and proposed-action staging. Purpose-built for clinical consultation and care coordination.

Order Management

Lab, medication, imaging, and biopsy orders with integrated safety checks, allergy verification, and drug interaction screening.

Diagnostic Workup

Structured genomics, staging assessments, and diagnostic profiles with automated order set generation based on diagnosis.

Care Team Collaboration

Patient-scoped messaging channels with threading, priority routing, and real-time coordination across multidisciplinary teams.

Built from the bedside

Zen Oncology is created by Jake Cotner, a Cell Therapy RN Coordinator who works on the front lines of cancer care every day. The product isn't built from assumptions about what clinicians need — it's built from lived experience navigating the gaps in existing systems while coordinating some of the most complex treatments in medicine.

When the tools you depend on to manage CAR-T patients, treatment pathways, and multidisciplinary coordination aren't built for the job, you either work around them or build something better.

Let's talk

Interested in learning more, exploring a partnership, or seeing a demo? Reach out directly.

jake@zenhealthsystems.com